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Fetal hemoglobin reactivation and cell engineering in the treatment of sickle cell anemia

The natural history of severe hemoglobinopathies like sickle cell disease (SCD) is rather variable, depending on the circumstances, but the main influence on such variability is the level of fetal hemoglobin (HbF) in the patient’s red cells. It is well known that a significant HbF level is associate...

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Detalles Bibliográficos
Autores principales: Eridani, Sandro, Mosca, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262355/
https://www.ncbi.nlm.nih.gov/pubmed/22287860
http://dx.doi.org/10.2147/JBM.S14942