HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast

BACKGROUND: Invasive micropapillary carcinoma (IMPC) of the breast is a distinct and aggressive variant of luminal type B breast cancer that does not respond to neoadjuvant chemotherapy. It is characterized by small pseudopapillary clusters of cancer cells with inverted cell polarity. To investigate...

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Detalles Bibliográficos
Autores principales: Doublier, Sophie, Belisario, Dimas C, Polimeni, Manuela, Annaratone, Laura, Riganti, Chiara, Allia, Elena, Ghigo, Dario, Bosia, Amalia, Sapino, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262753/
https://www.ncbi.nlm.nih.gov/pubmed/22217342
http://dx.doi.org/10.1186/1471-2407-12-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262753/
https://www.ncbi.nlm.nih.gov/pubmed/22217342
http://dx.doi.org/10.1186/1471-2407-12-4

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