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Mitochondrial DNA (mtDNA) haplogroups and serum levels of anti-oxidant enzymes in patients with osteoarthritis

BACKGROUND: Oxidative stress play a main role in the initiation and progression of the OA disease and leads to the degeneration of mitochondria. To prevent this, the chondrocytes possess a well-coordinated enzymatic antioxidant system. Besides, the mitochondrial DNA (mtDNA) haplogroups are associate...

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Detalles Bibliográficos
Autores principales: Fernandez-Moreno, Mercedes, Soto-Hermida, Angel, Pertega, Sonia, Oreiro, Natividad, Fernandez-Lopez, Carlos, Rego-Perez, Ignacio, Blanco, Francisco J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262769/
https://www.ncbi.nlm.nih.gov/pubmed/22108257
http://dx.doi.org/10.1186/1471-2474-12-264