HMGA1 Induces Intestinal Polyposis in Transgenic Mice and Drives Tumor Progression and Stem Cell Properties in Colon Cancer Cells

BACKGROUND: Although metastatic colon cancer is a leading cause of cancer death worldwide, the molecular mechanisms that enable colon cancer cells to metastasize remain unclear. Emerging evidence suggests that metastatic cells develop by usurping transcriptional networks from embryonic stem (ES) cel...

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Detalles Bibliográficos
Autores principales: Belton, Amy, Gabrovsky, Alexander, Bae, Young Kyung, Reeves, Ray, Iacobuzio-Donahue, Christine, Huso, David L., Resar, Linda M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262796/
https://www.ncbi.nlm.nih.gov/pubmed/22276142
http://dx.doi.org/10.1371/journal.pone.0030034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262796/
https://www.ncbi.nlm.nih.gov/pubmed/22276142
http://dx.doi.org/10.1371/journal.pone.0030034

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