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A Novel Role for BDNF-TrkB in the Regulation of Chemotherapy Resistance in Head and Neck Squamous Cell Carcinoma

Mechanisms of resistance for HNSCC to cisplatin (CDDP), the foundational chemotherapeutic agent in the treatment of this disease, remain poorly understood. We previously demonstrated that cisplatin resistance (CR) can be overcome by targeting Trk receptor. In the current study, we explored the poten...

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Detalles Bibliográficos
Autores principales: Lee, Junegoo, Jiffar, Tilahun, Kupferman, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262811/
https://www.ncbi.nlm.nih.gov/pubmed/22276165
http://dx.doi.org/10.1371/journal.pone.0030246