Cargando…
A Novel Role for BDNF-TrkB in the Regulation of Chemotherapy Resistance in Head and Neck Squamous Cell Carcinoma
Mechanisms of resistance for HNSCC to cisplatin (CDDP), the foundational chemotherapeutic agent in the treatment of this disease, remain poorly understood. We previously demonstrated that cisplatin resistance (CR) can be overcome by targeting Trk receptor. In the current study, we explored the poten...
Autores principales: | Lee, Junegoo, Jiffar, Tilahun, Kupferman, Michael E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262811/ https://www.ncbi.nlm.nih.gov/pubmed/22276165 http://dx.doi.org/10.1371/journal.pone.0030246 |
Ejemplares similares
-
Brain-Derived Neurotrophin and TrkB in Head and Neck Squamous Cell Carcinoma
por: Dudás, József, et al.
Publicado: (2019) -
Brain derived neutrophic factor (BDNF) coordinates lympho-vascular metastasis through a fibroblast-governed paracrine axis in the tumor microenvironment
por: Jiffar, Tilahun, et al.
Publicado: (2017) -
The Role of BDNF-TrkB Signaling in the Pathogenesis of PTSD
por: Green, Christopher R., et al.
Publicado: (2013) -
Do Small Molecules Activate the TrkB Receptor in the Same Manner as BDNF? Limitations of Published TrkB Low Molecular Agonists and Screening for Novel TrkB Orthosteric Agonists
por: Pankiewicz, Piotr, et al.
Publicado: (2021) -
TrkB/BDNF signalling patterns the sympathetic nervous system
por: Kasemeier-Kulesa, Jennifer C., et al.
Publicado: (2015)