Metabolic State Determines Sensitivity to Cellular Stress in Huntington Disease: Normalization by Activation of PPARγ

Impairments in mitochondria and transcription are important factors in the pathogenesis of Huntington disease (HD), a neurodegenerative disease caused by a polyglutamine expansion in the huntingtin protein. This study investigated the effect of different metabolic states and peroxisome proliferator-...

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Detalles Bibliográficos
Autores principales: Jin, Youngnam N., Hwang, Woong Y., Jo, Chulman, Johnson, Gail V. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262812/
https://www.ncbi.nlm.nih.gov/pubmed/22276192
http://dx.doi.org/10.1371/journal.pone.0030406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262812/
https://www.ncbi.nlm.nih.gov/pubmed/22276192
http://dx.doi.org/10.1371/journal.pone.0030406

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