Protein Kinase D1 Maintains the Epithelial Phenotype by Inducing a DNA-Bound, Inactive SNAI1 Transcriptional Repressor Complex

BACKGROUND: Protein Kinase D1 is downregulated in its expression in invasive ductal carcinoma of the breast and in invasive breast cancer cells, but its functions in normal breast epithelial cells is largely unknown. The epithelial phenotype is maintained by cell-cell junctions formed by E-cadherin....

Descripción completa

Detalles Bibliográficos
Autores principales: Bastea, Ligia I., Döppler, Heike, Balogun, Bolanle, Storz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262827/
https://www.ncbi.nlm.nih.gov/pubmed/22276203
http://dx.doi.org/10.1371/journal.pone.0030459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262827/
https://www.ncbi.nlm.nih.gov/pubmed/22276203
http://dx.doi.org/10.1371/journal.pone.0030459

Ejemplares similares