Mice completely lacking immunoproteasomes display major alterations in antigen presentation

The importance of immunoproteasomes to antigen presentation has been unclear because animals totally lacking immunoproteasomes have not been previously developed. Here we show that dendritic cells from mice lacking the three immunoproteasome catalytic subunits display defects in presenting multiple...

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Detalles Bibliográficos
Autores principales: Kincaid, Eleanor Z, Che, Jenny W, York, Ian, Escobar, Hernando, Reyes-Vargas, Eduardo, Delgado, Julio C., Welsh, Raymond M, Karow, Margaret L., Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Rock, Kenneth L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262888/
https://www.ncbi.nlm.nih.gov/pubmed/22197977
http://dx.doi.org/10.1038/ni.2203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262888/
https://www.ncbi.nlm.nih.gov/pubmed/22197977
http://dx.doi.org/10.1038/ni.2203

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