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Oncogenic activation of ERG: A predominant mechanism in prostate cancer

Prevalent gene fusions involving regulatory sequences of the androgen receptor (AR) regulated genes (primarily TMPRSS2) and protein coding sequences of nuclear transcription factors of the ETS gene family (predominantly ERG) result in unscheduled androgen dependent ERG expression in prostate cancer...

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Detalles Bibliográficos
Autores principales: Sreenath, Taduru L, Dobi, Albert, Petrovics, Gyorgy, Srivastava, Shiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263025/
https://www.ncbi.nlm.nih.gov/pubmed/22279422
http://dx.doi.org/10.4103/1477-3163.91122