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Investigation of glucose-modified liposomes using polyethylene glycols with different chain lengths as the linkers for brain targeting
BACKGROUND: An intimidating challenge to transporting drugs into the brain parenchyma is the presence of the blood–brain barrier (BBB). Glucose is an essential nutritional substance for brain function sustenance, which cannot be synthesized by the brain. Its transport primarily depends on the glucos...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263409/ https://www.ncbi.nlm.nih.gov/pubmed/22275832 http://dx.doi.org/10.2147/IJN.S23771 |