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RGD-modified poly(D,L-lactic acid) nanoparticles enhance tumor targeting of oridonin

OBJECTIVE: The purpose of this study was to develop an active targeting strategy to improve the therapeutic antitumor efficacy of oridonin (ORI), the main active ingredient in the medicinal herb Rabdosia rubescens. METHODS: A modified spontaneous emulsification solvent diffusion method was used to p...

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Detalles Bibliográficos
Autores principales: Xu, Jie, Zhao, Ji-Hui, Liu, Ying, Feng, Nian-Ping, Zhang, Yong-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263413/
https://www.ncbi.nlm.nih.gov/pubmed/22275836
http://dx.doi.org/10.2147/IJN.S27581