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Therapeutic Interventions Targeting Beta Amyloid Pathogenesis in an Aging Dog Model

Aged dogs and humans share complex cognitive and pathological responses to aging. Specifically, dogs develop Alzheimer’s Disease (AD) like beta-amyloid (Aβ) that are associated with cognitive deficits. Currently, therapeutic approaches to prevent AD are targeted towards reduced production, aggregati...

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Detalles Bibliográficos
Autores principales: Martin, Sarah B, Dowling, Amy L.S, Head, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263459/
https://www.ncbi.nlm.nih.gov/pubmed/22654723
http://dx.doi.org/10.2174/157015911798376217