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cGMP Signaling, Phosphodiesterases and Major Depressive Disorder

Deficits in neuroplasticity are hypothesized to underlie the pathophysiology of major depressive disorder (MDD): the effectiveness of antidepressants is thought to be related to the normalization of disrupted synaptic transmission and neurogenesis. The cyclic adenosine monophosphate (cAMP) signaling...

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Detalles Bibliográficos
Autores principales: Reierson, Gillian W, Guo, Shuyu, Mastronardi, Claudio, Licinio, Julio, Wong, Ma-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263465/
https://www.ncbi.nlm.nih.gov/pubmed/22654729
http://dx.doi.org/10.2174/157015911798376271