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Mechanisms of Brain Aging Regulation by Insulin: Implications for Neurodegeneration in Late-Onset Alzheimer's Disease

Insulin and IGF seem to be important players in modulating brain aging. Neurons share more similarities with islet cells than any other human cell type. Insulin and insulin receptors are diffusely found in the brain, especially so in the hippocampus. Caloric restriction decreases insulin resistance,...

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Detalles Bibliográficos
Autores principales: Schuh, Artur F., Rieder, Carlos M., Rizzi, Liara, Chaves, Márcia, Roriz-Cruz, Matheus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263551/
https://www.ncbi.nlm.nih.gov/pubmed/22389813
http://dx.doi.org/10.5402/2011/306905