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Role of HER2-Targeted Agents in Adjuvant Treatment for Breast Cancer
Approximately 20% of breast cancers overexpress human epidermal growth factor receptor 2 (HER2) protein, mainly as a result of gene amplification. The receptor tyrosine kinase is believed to play a critical role in the pathogenesis and further proliferation of these tumors. The application of trastu...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263614/ https://www.ncbi.nlm.nih.gov/pubmed/22295205 http://dx.doi.org/10.1155/2011/730360 |