Synthesis and Inhibiting Activity of Some 4-Hydroxycoumarin Derivatives on HIV-1 Protease

Six novel 4-hydroxycoumarin derivatives were rationally synthesized, verified, and characterized by molecular docking using crystal HIV-1 protease. Molecular docking studies predicted antiprotease activity of (7) and (10). The most significant functional groups, responsible for the interaction with...

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Detalles Bibliográficos
Autores principales: Stanchev, Stancho, Jensen, Frank, Hinkov, Anton, Atanasov, Vasil, Genova-Kalou, Petia, Argirova, Radka, Manolov, Ilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263710/
https://www.ncbi.nlm.nih.gov/pubmed/22389842
http://dx.doi.org/10.5402/2011/137637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263710/
https://www.ncbi.nlm.nih.gov/pubmed/22389842
http://dx.doi.org/10.5402/2011/137637

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