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Morphology and Release Kinetics of Protein-Loaded Porous Poly(L-Lactic Acid) Spheres Prepared by Freeze-Drying Technique

Freeze-drying a biodegradable polymer, poly(L-lactic acid) (PLLA), from 1,4-dioxane solutions provided very porous spherical particles of ca. 3 mm in radius with specific surface area of 8–13 m(2) g(−1). The surface of the particle was found to be less porous compared with its interior. To apply the...

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Detalles Bibliográficos
Autores principales: Sasaki, Takashi, Tanaka, Kazuki, Morino, Daisuke, Sakurai, Kensuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263714/
https://www.ncbi.nlm.nih.gov/pubmed/22389850
http://dx.doi.org/10.5402/2011/490567