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Formulation and Optimization of Sustained Release Stavudine Microspheres Using Response Surface Methodology

The aim of the current study was to formulate and optimize the formulation on the basis of in vitro performance of microsphere. A 3(2) full factorial design was employed to study the effect of independent variables, polymer-to-drug ratio (X (1)) and stirring speed (X (2)), on dependent variables, en...

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Detalles Bibliográficos
Autores principales: Dey, Sanjay, Pramanik, Soumen, Malgope, Ananya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263718/
https://www.ncbi.nlm.nih.gov/pubmed/22389855
http://dx.doi.org/10.5402/2011/627623