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Direct Detection and Sequencing of Damaged DNA Bases

Products of various forms of DNA damage have been implicated in a variety of important biological processes, such as aging, neurodegenerative diseases, and cancer. Therefore, there exists great interest to develop methods for interrogating damaged DNA in the context of sequencing. Here, we demonstra...

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Detalles Bibliográficos
Autores principales: Clark, Tyson A, Spittle, Kristi E, Turner, Stephen W, Korlach, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264494/
https://www.ncbi.nlm.nih.gov/pubmed/22185597
http://dx.doi.org/10.1186/2041-9414-2-10