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Subcellular Targeting Domains of Sphingomyelin Synthase 1 and 2

Sphingomyelin synthase (SMS) sits at the crossroads of sphingomyelin (SM), ceramide, diacylglycerol (DAG) metabolism. It utilizes ceramide and phosphatidylcholine as substrates to produce SM and DAG, thereby regulating lipid messengers which play a role in cell survival and apoptosis. Furthermore, i...

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Detalles Bibliográficos
Autores principales: Yeang, Calvin, Ding, Tingbo, Chirico, William J, Jiang, Xian-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264500/
https://www.ncbi.nlm.nih.gov/pubmed/22168400
http://dx.doi.org/10.1186/1743-7075-8-89