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Down-regulation of HSP70 sensitizes gastric epithelial cells to apoptosis and growth retardation triggered by H. pylori

BACKGROUND: H. pylori infection significantly attenuated the expression of HSP70 in gastric mucosal cells. However, the role of HSP70 cancellation in H. pylori-associated cell damages is largely unclear. METHODS: Small interfering RNA (siRNA) was used to down-regulate HSP70 in gastric epithelial cel...

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Detalles Bibliográficos
Autores principales: Liu, Weili, Chen, Yan, Lu, Gaofeng, Sun, Leimin, Si, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264526/
https://www.ncbi.nlm.nih.gov/pubmed/22208848
http://dx.doi.org/10.1186/1471-230X-11-146