GSVD Comparison of Patient-Matched Normal and Tumor aCGH Profiles Reveals Global Copy-Number Alterations Predicting Glioblastoma Multiforme Survival

Despite recent large-scale profiling efforts, the best prognostic predictor of glioblastoma multiforme (GBM) remains the patient's age at diagnosis. We describe a global pattern of tumor-exclusive co-occurring copy-number alterations (CNAs) that is correlated, possibly coordinated with GBM pati...

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Detalles Bibliográficos
Autores principales: Lee, Cheng H., Alpert, Benjamin O., Sankaranarayanan, Preethi, Alter, Orly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264559/
https://www.ncbi.nlm.nih.gov/pubmed/22291905
http://dx.doi.org/10.1371/journal.pone.0030098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264559/
https://www.ncbi.nlm.nih.gov/pubmed/22291905
http://dx.doi.org/10.1371/journal.pone.0030098

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