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Structure-Function Studies of DNA Binding Domain of Response Regulator KdpE Reveals Equal Affinity Interactions at DNA Half-Sites

Expression of KdpFABC, a K(+) pump that restores osmotic balance, is controlled by binding of the response regulator KdpE to a specific DNA sequence (kdpFABC(BS)) via the winged helix-turn-helix type DNA binding domain (KdpE(DBD)). Exploration of E. coli KdpE(DBD) and kdpFABC(BS) interaction resulte...

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Detalles Bibliográficos
Autores principales: Narayanan, Anoop, Paul, Lake N., Tomar, Sakshi, Patil, Dipak N., Kumar, Pravindra, Yernool, Dinesh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264566/
https://www.ncbi.nlm.nih.gov/pubmed/22291906
http://dx.doi.org/10.1371/journal.pone.0030102