Increased Expression of PcG Protein YY1 Negatively Regulates B Cell Development while Allowing Accumulation of Myeloid Cells and LT-HSC Cells

Ying Yang 1 (YY1) is a multifunctional Polycomb Group (PcG) transcription factor that binds to multiple enhancer binding sites in the immunoglobulin (Ig) loci and plays vital roles in early B cell development. PcG proteins have important functions in hematopoietic stem cell renewal and YY1 is the on...

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Detalles Bibliográficos
Autores principales: Pan, Xuan, Jones, Morgan, Jiang, Jie, Zaprazna, Kristina, Yu, Duonan, Pear, Warren, Maillard, Ivan, Atchison, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264595/
https://www.ncbi.nlm.nih.gov/pubmed/22292011
http://dx.doi.org/10.1371/journal.pone.0030656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264595/
https://www.ncbi.nlm.nih.gov/pubmed/22292011
http://dx.doi.org/10.1371/journal.pone.0030656

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