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Optimal Population of FoxP3(+) T Cells in Tumors Requires an Antigen Priming-Dependent Trafficking Receptor Switch

FoxP3(+) T cells populate tumors and regulate anti-tumor immunity. The requirement for optimal population of FoxP3(+) regulatory T cells in tumors remains unclear. We investigated the migration requirement and stability of tumor-associated FoxP3(+) T cells. We found that only memory, but not naïve,...

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Detalles Bibliográficos
Autores principales: Wang, Chuanwu, Lee, Jee H., Kim, Chang H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264621/
https://www.ncbi.nlm.nih.gov/pubmed/22292042
http://dx.doi.org/10.1371/journal.pone.0030793