The Prosensory Function of Sox2 in the Chicken Inner Ear Relies on the Direct Regulation of Atoh1

The proneural gene Atoh1 is crucial for the development of inner ear hair cells and it requires the function of the transcription factor Sox2 through yet unknown mechanisms. In the present work, we used the chicken embryo and HEK293T cells to explore the regulation of Atoh1 by Sox2. The results show...

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Detalles Bibliográficos
Autores principales: Neves, Joana, Uchikawa, Masanori, Bigas, Anna, Giraldez, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264626/
https://www.ncbi.nlm.nih.gov/pubmed/22292066
http://dx.doi.org/10.1371/journal.pone.0030871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264626/
https://www.ncbi.nlm.nih.gov/pubmed/22292066
http://dx.doi.org/10.1371/journal.pone.0030871

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