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The Prosensory Function of Sox2 in the Chicken Inner Ear Relies on the Direct Regulation of Atoh1
The proneural gene Atoh1 is crucial for the development of inner ear hair cells and it requires the function of the transcription factor Sox2 through yet unknown mechanisms. In the present work, we used the chicken embryo and HEK293T cells to explore the regulation of Atoh1 by Sox2. The results show...
Autores principales: | Neves, Joana, Uchikawa, Masanori, Bigas, Anna, Giraldez, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264626/ https://www.ncbi.nlm.nih.gov/pubmed/22292066 http://dx.doi.org/10.1371/journal.pone.0030871 |
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