Novel Strategy for Selection of Monoclonal Antibodies Against Highly Conserved Antigens: Phage Library Panning Against Ephrin-B2 Displayed on Yeast

Ephrin-B2 is predominately expressed in endothelium of arterial origin, involved in developmental angiogenesis and neovasculature formation through its interaction with EphB4. Despite its importance in physiology and pathological conditions, it has been challenging to produce monoclonal antibodies a...

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Detalles Bibliográficos
Autores principales: Gu, Xiaoling, Vedvyas, Yogindra, Chen, Xiaoyue, Kaushik, Tanwi, Hwang, Chang-Il, Hu, Xuebo, Nikitin, Alexander Y., Jin, Moonsoo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264634/
https://www.ncbi.nlm.nih.gov/pubmed/22292016
http://dx.doi.org/10.1371/journal.pone.0030680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264634/
https://www.ncbi.nlm.nih.gov/pubmed/22292016
http://dx.doi.org/10.1371/journal.pone.0030680

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