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Novel Strategy for Selection of Monoclonal Antibodies Against Highly Conserved Antigens: Phage Library Panning Against Ephrin-B2 Displayed on Yeast
Ephrin-B2 is predominately expressed in endothelium of arterial origin, involved in developmental angiogenesis and neovasculature formation through its interaction with EphB4. Despite its importance in physiology and pathological conditions, it has been challenging to produce monoclonal antibodies a...
Autores principales: | Gu, Xiaoling, Vedvyas, Yogindra, Chen, Xiaoyue, Kaushik, Tanwi, Hwang, Chang-Il, Hu, Xuebo, Nikitin, Alexander Y., Jin, Moonsoo M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264634/ https://www.ncbi.nlm.nih.gov/pubmed/22292016 http://dx.doi.org/10.1371/journal.pone.0030680 |
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