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Vaccination-induced changes in human B-cell repertoire and pneumococcal IgM and IgA antibody at different ages

It is well known that older people are more susceptible to morbidity and mortality from infectious diseases, particularly from pulmonary diseases such as pneumococcal pneumonia where vaccines do not provide efficient protection as in younger populations. We have previously shown that the B-cell repe...

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Detalles Bibliográficos
Autores principales: Ademokun, Alexander, Wu, Yu-Chang, Martin, Victoria, Mitra, Rajive, Sack, Ulrich, Baxendale, Helen, Kipling, David, Dunn-Walters, Deborah K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264704/
https://www.ncbi.nlm.nih.gov/pubmed/21726404
http://dx.doi.org/10.1111/j.1474-9726.2011.00732.x