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TRIM5α and Species Tropism of HIV/SIV

Human immunodeficiency virus type 1 (HIV-1) infects humans and chimpanzees but not old world monkeys (OWMs) such as the rhesus monkey (Rh) and cynomolgus monkey (CM). HIV-1 efficiently enters cells of OWMs but encounters a block before reverse transcription. This narrow host range is attributed to a...

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Detalles Bibliográficos
Autores principales: Nakayama, Emi E., Shioda, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264904/
https://www.ncbi.nlm.nih.gov/pubmed/22291694
http://dx.doi.org/10.3389/fmicb.2012.00013