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Quantitative Assessment of Protein Interaction with Methyl-Lysine Analogues by Hybrid Computational and Experimental Approaches

[Image: see text] In cases where binding ligands of proteins are not easily available, structural analogues are often used. For example, in the analysis of proteins recognizing different methyl-lysine residues in histones, methyl-lysine analogues based on methyl-amino-alkylated cysteine residues hav...

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Detalles Bibliográficos
Autores principales: Seeliger, Daniel, Soeroes, Szabolcs, Klingberg, Rebecca, Schwarzer, Dirk, Grubmüller, Helmut, Fischle, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265130/
https://www.ncbi.nlm.nih.gov/pubmed/21991995
http://dx.doi.org/10.1021/cb200363r