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Ursodeoxycholic acid prevents selenite-induced oxidative stress and alleviates cataract formation: In vitro and in vivo studies

OBJECTIVE: To evaluate the antioxidative and anticataractogenic potential effect of ursodeoxycholic acid (UDCA) on selenite-induced cataract in vitro and in vivo. METHODS: Enucleated rat lenses were incubated in M199 medium alone (Group I), with 200 μM selenite (Group II), or with 200 μM selenite an...

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Detalles Bibliográficos
Autores principales: Qi, Hui-Ping, Wei, Shu-Qin, Gao, Xiang-Chun, Yu, Nan-Nan, Hu, Wan-Zhen, Bi, Sheng, Cui, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265174/
https://www.ncbi.nlm.nih.gov/pubmed/22275806