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Accumulation and autofluorescence of phagocytized rod outer segment material in macrophages and microglial cells

PURPOSE: To explore the ability of macrophages and microglial cells to phagocytize rod outer segments (ROSs) in a cell culture and characterize the resulting lipofuscin-like autofluorescence (LLAF). METHODS: Either regular or modified ROSs or ROS components (11-cis-retinal, all-trans-retinal, lipids...

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Detalles Bibliográficos
Autores principales: Lei, Lei, Tzekov, Radouil, Tang, Shibo, Kaushal, Shalesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265176/
https://www.ncbi.nlm.nih.gov/pubmed/22275801