Cargando…

Cisplatin Tumor Biodistribution and Efficacy after Intratumoral Injection of a Biodegradable Extended Release Implant

Local delivery of chemotherapeutic drugs has long been recognized as a potential method for reaching high drug doses at the target site while minimizing systemic exposure. Cisplatin is one of the most effective chemotherapeutic agents for the treatment of various tumors; however, its systemic toxici...

Descripción completa

Detalles Bibliográficos
Autores principales: Shikanov, Ariella, Shikanov, Sergey, Vaisman, Boris, Golenser, Jacob, Domb, Abraham J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265254/
https://www.ncbi.nlm.nih.gov/pubmed/22295203
http://dx.doi.org/10.1155/2011/175054