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Cisplatin Tumor Biodistribution and Efficacy after Intratumoral Injection of a Biodegradable Extended Release Implant
Local delivery of chemotherapeutic drugs has long been recognized as a potential method for reaching high drug doses at the target site while minimizing systemic exposure. Cisplatin is one of the most effective chemotherapeutic agents for the treatment of various tumors; however, its systemic toxici...
Autores principales: | Shikanov, Ariella, Shikanov, Sergey, Vaisman, Boris, Golenser, Jacob, Domb, Abraham J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265254/ https://www.ncbi.nlm.nih.gov/pubmed/22295203 http://dx.doi.org/10.1155/2011/175054 |
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