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Plasmodium falciparum: Assessment of Selectivity of Action of Chloroquine, Alchornea cordifolia, Ficus polita, and Other Drugs by a Tetrazolium-Based Colorimetric Assay

A tetrazolium-based colorimetric selective assay (MTT-based CSA) was developed to assess the selectivity of antimalarial drugs. This in vitro assay, unlike all others, measures the ability of drugs to indirectly protect red blood cells (RBCs) from Plasmodium-falciparum-induced destruction. Optimum i...

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Detalles Bibliográficos
Autores principales: Ayisi, Nana Kofi, Appiah-Opong, Regina, Gyan, Ben, Bugyei, Kwasi, Ekuban, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265290/
https://www.ncbi.nlm.nih.gov/pubmed/22312574
http://dx.doi.org/10.4061/2011/816250