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Artificial 64-Residue HIV-1 Enhancer-Binding Peptide Is a Potent Inhibitor of Viral Replication in HIV-1-Infected Cells

An artificial HIV-1 enhancer-binding peptide was extended by nine consecutive arginine residues at the C-terminus and by the nuclear localization signal of SV40 large T antigen at the N-terminus. The resulting synthetic 64-residue peptide was found to bind to the two enhancers of the HIV-1 long term...

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Detalles Bibliográficos
Autores principales: Oufir, Mouhssin, Bisset, Leslie R., Hoffmann, Stefan R. K., Xue, Gongda, Klauser, Stephan, Bergamaschi, Bianca, Gervaix, Alain, Böni, Jürg, Schüpbach, Jörg, Gutte, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265293/
https://www.ncbi.nlm.nih.gov/pubmed/22312334
http://dx.doi.org/10.1155/2011/165871