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Bacterial Toxin Fusion Proteins Elicit Mucosal Immunity against a Foot-and-Mouth Disease Virus Antigen When Administered Intranasally to Guinea Pigs

Peptides corresponding to the foot-and-mouth disease virus VP1 G-H loop are capable of inducing neutralizing antibodies in some species but are considered relatively poor immunogens, especially at mucosal surfaces. However, intranasal administration of antigens along with the appropriate delivery ve...

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Detalles Bibliográficos
Autores principales: Challa, Sreerupa, Szczepanek, Steven M., Rood, Debra, Barrette, Roger W., Silbart, Lawrence K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265312/
https://www.ncbi.nlm.nih.gov/pubmed/22312350
http://dx.doi.org/10.1155/2011/713769