Elicitation of Neutralizing Antibodies Directed against CD4-Induced Epitope(s) Using a CD4 Mimetic Cross-Linked to a HIV-1 Envelope Glycoprotein

The identification of HIV-1 envelope glycoprotein (Env) structures that can generate broadly neutralizing antibodies (BNAbs) is pivotal to the development of a successful vaccine against HIV-1 aimed at eliciting effective humoral immune responses. To that end, the production of novel Env structure(s...

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Detalles Bibliográficos
Autores principales: Dey, Antu K., Burke, Brian, Sun, Yide, Sirokman, Klara, Nandi, Avishek, Hartog, Karin, Lian, Ying, Geonnotti, Anthony R., Montefiori, David, Franti, Michael, Martin, Grégoire, Carfi, Andrea, Kessler, Pascal, Martin, Loïc, Srivastava, Indresh K., Barnett, Susan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265465/
https://www.ncbi.nlm.nih.gov/pubmed/22291921
http://dx.doi.org/10.1371/journal.pone.0030233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265465/
https://www.ncbi.nlm.nih.gov/pubmed/22291921
http://dx.doi.org/10.1371/journal.pone.0030233

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