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A Flexible Model of HIV-1 Latency Permitting Evaluation of Many Primary CD4 T-Cell Reservoirs

Latently infected cells form the major obstacle to HIV eradication. Studies of HIV latency have been generally hindered by the lack of a robust and rapidly deployable cell model that involves primary human CD4 T lymphocytes. Latently infected cell lines have proven useful, but it is unclear how clos...

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Detalles Bibliográficos
Autores principales: Lassen, Kara G., Hebbeler, Andrew M., Bhattacharyya, Darshana, Lobritz, Michael A., Greene, Warner C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265466/
https://www.ncbi.nlm.nih.gov/pubmed/22291913
http://dx.doi.org/10.1371/journal.pone.0030176