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Stochastic Expression of the Interferon-β Gene

Virus infection of mammalian cells induces the production of high levels of type I interferons (IFNα and β), cytokines that orchestrate antiviral innate and adaptive immunity. Previous studies have shown that only a fraction of the infected cells produce IFN. However, the mechanisms responsible for...

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Detalles Bibliográficos
Autores principales: Zhao, Mingwei, Zhang, Jiangwen, Phatnani, Hemali, Scheu, Stefanie, Maniatis, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265471/
https://www.ncbi.nlm.nih.gov/pubmed/22291574
http://dx.doi.org/10.1371/journal.pbio.1001249