Novel AlkB Dioxygenases—Alternative Models for In Silico and In Vivo Studies

BACKGROUND: ALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a direct, single-protein repair system, protecting cellular DNA and RNA against the cytotoxic and mutagenic activity of alkylating agents, chemicals significantly contributing to tumor formation and used in can...

Descripción completa

Detalles Bibliográficos
Autores principales: Mielecki, Damian, Zugaj, Dorota Ł., Muszewska, Anna, Piwowarski, Jan, Chojnacka, Aleksandra, Mielecki, Marcin, Nieminuszczy, Jadwiga, Grynberg, Marcin, Grzesiuk, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265494/
https://www.ncbi.nlm.nih.gov/pubmed/22291995
http://dx.doi.org/10.1371/journal.pone.0030588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265494/
https://www.ncbi.nlm.nih.gov/pubmed/22291995
http://dx.doi.org/10.1371/journal.pone.0030588

Ejemplares similares