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Selective Induction of Cell Death in Melanoma Cell Lines through Targeting of Mcl-1 and A1

Melanoma is an often fatal form of skin cancer which is remarkably resistant against radio- and chemotherapy. Even new strategies that target RAS/RAF signaling and display unprecedented efficacy are characterized by resistance mechanisms. The targeting of survival pathways would be an attractive alt...

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Detalles Bibliográficos
Autores principales: Senft, Daniela, Berking, Carola, Graf, Saskia A., Kammerbauer, Claudia, Ruzicka, Thomas, Besch, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265511/
https://www.ncbi.nlm.nih.gov/pubmed/22292048
http://dx.doi.org/10.1371/journal.pone.0030821