Cargando…

miR-16 Targets Transcriptional Corepressor SMRT and Modulates NF-kappaB-Regulated Transactivation of Interleukin-8 Gene

The signaling pathways associated with the Toll-like receptors (TLRs) and nuclear factor-kappaB (NF-κB) are essential to pro-inflammatory cytokine and chemokine expression, as well as initiating innate epithelial immune responses. The TLR/NF-κB signaling pathways must be stringently controlled throu...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Rui, Li, Xiaoqing, Hu, Guoku, Gong, Ai-Yu, Drescher, Kristen M., Chen, Xian-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265513/
https://www.ncbi.nlm.nih.gov/pubmed/22292036
http://dx.doi.org/10.1371/journal.pone.0030772