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The Role of Cilostazol, a Phosphodiesterase 3 Inhibitor, on Oocyte Maturation and Subsequent Pregnancy in Mice

It is important to identify effective contraceptive drugs that cause minimal disruption to physiological processes. Phosphodiesterase 3 (PDE3) inhibitors suppress meiosis in oocytes by decreasing the level of cAMP and blocking the extrusion of the first polar body. In this study, we tested the PDE3...

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Detalles Bibliográficos
Autores principales: Li, Min, Yu, Yang, Yan, Jie, Yan, Li-Ying, Zhao, Yue, Li, Rong, Liu, Ping, Hsueh, Aaron J., Qiao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265514/
https://www.ncbi.nlm.nih.gov/pubmed/22292006
http://dx.doi.org/10.1371/journal.pone.0030649