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Expression of Neurog1 Instead of Atoh1 Can Partially Rescue Organ of Corti Cell Survival

In the mammalian inner ear neurosensory cell fate depends on three closely related transcription factors, Atoh1 for hair cells and Neurog1 and Neurod1 for neurons. We have previously shown that neuronal cell fate can be altered towards hair cell fate by eliminating Neurod1 mediated repression of Ato...

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Detalles Bibliográficos
Autores principales: Jahan, Israt, Pan, Ning, Kersigo, Jennifer, Calisto, Lilian E., Morris, Ken A., Kopecky, Benjamin, Duncan, Jeremy S., Beisel, Kirk W., Fritzsch, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265522/
https://www.ncbi.nlm.nih.gov/pubmed/22292060
http://dx.doi.org/10.1371/journal.pone.0030853