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COUP-TFII Controls Mouse Pancreatic β-Cell Mass through GLP-1-β-Catenin Signaling Pathways

BACKGROUND: The control of the functional pancreatic β-cell mass serves the key homeostatic function of releasing the right amount of insulin to keep blood sugar in the normal range. It is not fully understood though how β-cell mass is determined. METHODOLOGY/PRINCIPAL FINDINGS: Conditional chicken...

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Detalles Bibliográficos
Autores principales: Boutant, Marie, Ramos, Oscar Henrique Pereira, Tourrel-Cuzin, Cécile, Movassat, Jamileh, Ilias, Anissa, Vallois, David, Planchais, Julien, Pégorier, Jean-Paul, Schuit, Frans, Petit, Patrice X., Bossard, Pascale, Maedler, Kathrin, Grapin-Botton, Anne, Vasseur-Cognet, Mireille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265526/
https://www.ncbi.nlm.nih.gov/pubmed/22292058
http://dx.doi.org/10.1371/journal.pone.0030847