The HIV1 Protein Vpr Acts to Enhance Constitutive DCAF1-Dependent UNG2 Turnover

BACKGROUND: The HIV1 protein Vpr assembles with and acts through an ubiquitin ligase complex that includes DDB1 and cullin 4 (CRL4) to cause G2 cell cycle arrest and to promote degradation of both uracil DNA glycosylase 2 (UNG2) and single-strand selective mono-functional uracil DNA glycosylase 1 (S...

Descripción completa

Detalles Bibliográficos
Autores principales: Wen, Xiaoyun, Casey Klockow, Laurieann, Nekorchuk, Michael, Sharifi, Hamayun J., de Noronha, Carlos M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265533/
https://www.ncbi.nlm.nih.gov/pubmed/22292079
http://dx.doi.org/10.1371/journal.pone.0030939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265533/
https://www.ncbi.nlm.nih.gov/pubmed/22292079
http://dx.doi.org/10.1371/journal.pone.0030939

Ejemplares similares